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Renal Transplantation is the ultimate treatment for a patient of Permanent kidney failure. When compared to life long dialysis, Renal Transplantation offers the best possible quality of life. Renal transplantation is of two types. One is known as the live related transplantation where in the biologically related immediate family members would donate the kidney. The other type of transplantation is the Deceased Donor Transplantation wherein the kidney from a Brain Death Donors. At AINU, the transplant protocols aim for optimisation of immunosuppression so as to achieve the best long term outcomes. AINU has set a world class benchmark with regard to laparoscopic donor nephrectomy. In this technique, the donor can resume normal life style at the earliest when compared to the conventional open donor technique.